作者
Xin Chen, Poonguzhali Selvaraj, Lili Lin, Wenqin Fang, Congxian Wu, Piao Yang, Jing Zhang, Yakubu Saddeeq Abubakar, Fan Yang, Wende Liu, Zonghua Wang, Naweed I. Naqvi, Wenhui Zheng
发表日期
2023/8
期刊
New Phytologist
出版商
New Phytologist © 2023 New Phytologist Foundation
简介
- Secretion is a fundamental process that plant pathogens utilize to deliver effectors into the host to downregulate immunity and promote infection.
- Here, we uncover a fascinating membrane trafficking and delivery route that originates from vacuolar membranes in Magnaporthe oryzae and conduits to the host interface and plasma membrane.
- To perform such secretory/trafficking function, MoRab7 first recruits the retromer complex to the vacuolar membrane, enabling recognition of a family of SNARE proteins, including MoSnc1. Live‐cell imaging confirmed a highly dynamic vesicular trafficking of the retromer complex component(s) and MoSnc1 toward and across the host interface or plasma membrane, and subsequent fusion with target membranes. Interestingly, disruption of the MoRab7/Retromer/MoSnc1‐based endolysosomal cascade affects effector secretion and fungal pathogenicity.
- Taken together, we …
学术搜索中的文章
X Chen, P Selvaraj, L Lin, W Fang, C Wu, P Yang… - New Phytologist, 2023