作者
Inès Dufour, Thierry Duprez, Marie Wertz, Pascale Saussoy, Nathalie Ackermans, Souraya El Sankari, Vincent Van Pesch, Eric Van Den Neste
发表日期
2020/11
期刊
EJHaem
卷号
1
期号
2
页码范围
585-588
简介
Progressive multifocal leukoencephalopathy (PML) may develop in follicular lymphoma patients treated with bendamustine‐rituximab. In this report, treatment with pembrolizumab successfully inhibited the clinical progression of PML by promoting radiologically demonstrated immune restoration inflammatory syndrome (IRIS), allowing complete clearance of the virus. These findings may further support the use of pembrolizumab in PML with special consideration for the potential occurrence of IRIS.
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I Dufour, T Duprez, M Wertz, P Saussoy, N Ackermans… - EJHaem, 2020