作者
J Ruben Rodriguez, Roberto Salvia, Stefano Crippa, Andrew L Warshaw, Claudio Bassi, Massimo Falconi, Sarah P Thayer, Gregory Y Lauwers, Paola Capelli, Mari Mino–Kenudson, Oswaldo Razo, Deborah McGrath, Paolo Pederzoli, Carlos Fernández–Del Castillo
发表日期
2007/7/1
期刊
Gastroenterology
卷号
133
期号
1
页码范围
72-79
出版商
WB Saunders
简介
Background & Aims
Intraductal papillary mucinous neoplasms (IPMNs) of the pancreas arising in branch ducts are thought to be less aggressive than their main-duct counterparts, and guidelines for their conservative management were recently proposed. This study describes the combined experience of 2 tertiary centers with branch-duct IPMNs aiming to validate these recommendations.
Methods
A review of 145 patients with resected, pathologically confirmed, branch-duct IPMNs between 1990 and 2005 was conducted.
Results
Sixty-six patients (45.5%) had adenoma, 47 (32%) borderline tumors, 16 (11%) carcinoma in situ, and 16 (11%) invasive carcinoma. Median age was similar between benign and malignant subgroups (66 vs 67.5 years, respectively). Jaundice was more frequent in patients with cancer (12.5% vs 1.8%, respectively, P = .022) and abdominal pain in patients with benign tumors (45% vs 25 …
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JR Rodriguez, R Salvia, S Crippa, AL Warshaw… - Gastroenterology, 2007