作者
Carla Torrent, Caterina del Mar Bonnin, Anabel Martínez-Arán, Jesús Valle, Benedikt L Amann, Ana González-Pinto, José Manuel Crespo, Ángela Ibáñez, Mari Paz Garcia-Portilla, Rafael Tabarés-Seisdedos, Celso Arango, Francesc Colom, Brisa Sole, Isabella Pacchiarotti, Adriane R Rosa, Jose Luis Ayuso-Mateos, Celia Anaya, Patricia Fernandez, Ramon Landin-Romero, Silvia Alonso-Lana, Jordi Ortiz-Gil, Barbara Segura, Sara Barbeito, Patricia Vega, Miryam Fernandez, Amaia Ugarte, Marta Subira, Ester Cerrillo, Nuria Custal, Jose Manuel Menchon, Jeronimo Saiz-Ruiz, Jose Maria Rodao, Sandra Isella, Analucia Alegria, Susana Al-Halabi, Julio Bobes, Gonzalo Galvan, Pilar A Saiz, Vicent Balanza-Martinez, Gabriel Selva, Inmaculada Fuentes-Dura, Patricia Correa, Maria Mayoral, Guadalupe Chiclana, Jessica Merchan-Naranjo, Marta Rapado-Castro, Manel Salamero, Eduard Vieta
发表日期
2013/8
期刊
American Journal of Psychiatry
卷号
170
期号
8
页码范围
852-859
出版商
American Psychiatric Association
简介
Objective
The authors sought to assess the efficacy of functional remediation, a novel intervention program, on functional improvement in a sample of euthymic patients with bipolar disorder.
Method
In a multicenter, randomized, rater-blind clinical trial involving 239 outpatients with DSM-IV bipolar disorder, functional remediation (N=77) was compared with psychoeducation (N=82) and treatment as usual (N=80) over 21 weeks. Pharmacological treatment was kept stable in all three groups. The primary outcome measure was improvement in global psychosocial functioning, measured blindly as the mean change in score on the Functioning Assessment Short Test from baseline to endpoint.
Results
At the end of the study, 183 patients completed the treatment phase. Repeated-measures analysis revealed significant functional improvement from baseline to endpoint over the 21 weeks of treatment (last observation …
学术搜索中的文章
C Torrent, CM Bonnin, A Martínez-Arán, J Valle… - American Journal of Psychiatry, 2013