作者
Ali Almasirad, Sayyed A Tabatabai, Mehrdad Faizi, Abbas Kebriaeezadeh, Nazila Mehrabi, Afshin Dalvandi, Abbas Shafiee
发表日期
2004/12/20
期刊
Bioorganic & medicinal chemistry letters
卷号
14
期号
24
页码范围
6057-6059
出版商
Pergamon
简介
A series of new 2-substituted-5-[2-(2-fluorophenoxy)phenyl]-1,3,4-oxadiazoles has been synthesized and screened for their anticonvulsant activities. Compound 3 shows considerable anticonvulsant activity both in PTZ and MES models. It seems that this effect is mediated by benzodiazepine receptors and other unknown mechanism, respectively.
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A Almasirad, SA Tabatabai, M Faizi, A Kebriaeezadeh… - Bioorganic & medicinal chemistry letters, 2004