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The efficacy of furfural C5H4O2 (2-furaldehyde) extracted from corn cobs on germination and mycelial growth of the sclerotia of Sclerotinia sclerotiorum (Lib) DeBary isolated from infected eggplant plants, when mixed with PDA media before sterilization was studied. The results showed that germination of the sclerotia was delayed and suppressed, formed mycelium from it was inhibited by furfural concentrations 500-5000 ppm. Also it’s reduced the number of sclerotia per plate and delay it, the concentration 3000 ppm caused delay of the sclerotia production and their maturation. The dry weight of sclerotia per plate was significantly reduced in high concentrations of furfural (2000 and 3000 ppm).