作者
Allison W Kurian, Daphne Y Lichtensztajn, Theresa HM Keegan, David O Nelson, Christina A Clarke, Scarlett L Gomez
发表日期
2014/9/3
期刊
Jama
卷号
312
期号
9
页码范围
902-914
出版商
American Medical Association
简介
Importance
Bilateral mastectomy is increasingly used to treat unilateral breast cancer. Because it may have medical and psychosocial complications, a better understanding of its use and outcomes is essential to optimizing cancer care.
Objective
To compare use of and mortality after bilateral mastectomy, breast-conserving therapy with radiation, and unilateral mastectomy.
Design, Setting, and Participants
Observational cohort study within the population-based California Cancer Registry; participants were women diagnosed with stages 0-III unilateral breast cancer in California from 1998 through 2011, with median follow-up of 89.1 months.
Main Outcomes and Measures
Factors associated with surgery use (from polytomous logistic regression); overall and breast cancer–specific mortality (from propensity score weighting and Cox proportional hazards analysis).
Results
Among 189 734 patients, the rate of bilateral …
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AW Kurian, DY Lichtensztajn, THM Keegan, DO Nelson… - Jama, 2014