作者
Sylvia K Plevritis, Diego Munoz, Allison W Kurian, Natasha K Stout, Oguzhan Alagoz, Aimee M Near, Sandra J Lee, Jeroen J Van Den Broek, Xuelin Huang, Clyde B Schechter, Brian L Sprague, Juhee Song, Harry J De Koning, Amy Trentham-Dietz, Nicolien T Van Ravesteyn, Ronald Gangnon, Young Chandler, Yisheng Li, Cong Xu, Mehmet Ali Ergun, Hui Huang, Donald A Berry, Jeanne S Mandelblatt
发表日期
2018/1/9
期刊
Jama
卷号
319
期号
2
页码范围
154-164
出版商
American Medical Association
简介
Importance
Given recent advances in screening mammography and adjuvant therapy (treatment), quantifying their separate and combined effects on US breast cancer mortality reductions by molecular subtype could guide future decisions to reduce disease burden.
Objective
To evaluate the contributions associated with screening and treatment to breast cancer mortality reductions by molecular subtype based on estrogen-receptor (ER) and human epidermal growth factor receptor 2 (ERBB2, formerlyHER2orHER2/neu).
Design, Setting, and Participants
Six Cancer Intervention and Surveillance Network (CISNET) models simulated US breast cancer mortality from 2000 to 2012 using national data on plain-film and digital mammography patterns and performance, dissemination and efficacy of ER/ERBB2-specific treatment, and competing mortality. Multiple US birth cohorts were simulated.
Exposures
Screening …
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