作者
Gédéon Prince Manouana, Moustapha Nzamba Maloum, Rodrigue Bikangui, Sam O'neilla Oye Bingono, Georgelin Ondo Nguema, Josiane Yabo Honkpehedji, Elie Gide Rossatanga, Samira Zoa-Assoumou, Srinivas Reddy Pallerla, Sivaramakrishna Rachakonda, Armel Ndong Mintsa, Jean-Bernard Lekana-Douki, Joël-Fleury Djoba Siawaya, Steffen Borrmann, Peter Gottfried Kremsner, Bertrand Lell, Thirumalaisamy P Velavan, Ayola Akim Adegnika
发表日期
2022/1/1
期刊
International Journal of Infectious Diseases
卷号
114
页码范围
151-154
出版商
Elsevier
简介
Objective
Variants of concern (VOCs) associated with relatively high transmissibility appear to be rapidly spreading in Gabon. Therefore, it is imperative to understand the distribution of several VOCs in the population, which could have implications for transmissibility and vaccine efficacy.
Methods
Between February and May 2021, SARS-CoV-2 genomes were sequenced using the Oxford nanopore MinION method and the respective genome diversity was elucidated. Phylogenetic analysis was performed and genomes were classified using pangolin lineages.
Results
The results highlighted an increase (46%) in the alpha VOC (B.1.1.7) in the Gabonese population over the study period. In addition, an increase (31%) in the B.1.1.318 lineage, which is associated with high transmission and impaired vaccine efficacy (D614G+E484K+Y144del), was detected.
Conclusion
With the second wave ongoing, these findings …
学术搜索中的文章
GP Manouana, MN Maloum, R Bikangui, SOO Bingono… - International Journal of Infectious Diseases, 2022