查看文章

Rheumatoid arthritis (RA) is associated with a variety of kidney disorders. However, it is unclear whether the development of reduced kidney function is higher in patients with RA compared to the general population.

Retrospective review.

Incident adult-onset RA cases (813) and a comparison cohort of non-RA individuals (813) in Olmsted County, MN, in 1980-2007.

Baseline demographic and clinical variables.

Reduced kidney function: (1) estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73 m² and (2) eGFR < 45 mL/min/1.73 m² on 2 consecutive occasions at least 90 days apart; cardiovascular disease (CVD); and death.

The cumulative incidence of reduced kidney function was estimated adjusting for the competing risk of death.

Of 813 patients with RA and 813 non-RA individuals, mean age was 56 ± 16 (SD) years, 68 …