作者
Stephanie B Wheeler, Jennifer Spencer, Laura C Pinheiro, Caitlin C Murphy, Jo Anne Earp, Lisa Carey, Andrew Olshan, Chiu Kit Tse, Mary E Bell, Morris Weinberger, Katherine E Reeder-Hayes
发表日期
2019/5/1
期刊
JNCI: Journal of the National Cancer Institute
卷号
111
期号
5
页码范围
498-508
出版商
Oxford University Press
简介
Background
Differential use of endocrine therapy (ET) by race may contribute to breast cancer outcome disparities, but racial differences in ET behaviors are poorly understood.
Methods
Women aged 20–74 years with a first primary, stage I–III, hormone receptor–positive (HR+) breast cancer were included. At 2 years postdiagnosis, we assessed nonadherence, defined as not taking ET every day or missing more than two pills in the past 14 days, discontinuation, and a composite measure of underuse, defined as either missing pills or discontinuing completely. Using logistic regression, we evaluated the relationship between race and nonadherence, discontinuation, and overall underuse in unadjusted, clinically adjusted, and socioeconomically adjusted models.
Results
A total of 1280 women were included; 43.2% self-identified as black. Compared to …
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