作者
Emir Festic, Vikas Bansal, Daryl J Kor, Ognjen Gajic, US Critical Illness and Injury Trials Group: Lung Injury Prevention Study Investigators (USCIITG–LIPS)
发表日期
2015/5
期刊
Journal of intensive care medicine
卷号
30
期号
4
页码范围
209-216
出版商
SAGE Publications
简介
Purpose
Oxygen saturation to fraction of inspired oxygen ratio (SpO2/FiO2) has been validated as a surrogate marker for partial pressure of oxygen to fraction of inspired oxygen ratio among mechanically ventilated patients with acute respiratory distress syndrome (ARDS). The validity of SpO2/FiO2 measurements in predicting ARDS has not been studied. Recently, a Lung Injury Prediction Score (LIPS) has been developed to help identify patients at risk of developing ARDS.
Methods
This was a secondary analysis of the LIPS-1 cohort. A multivariate logistic regression included all established variables for LIPS, Acute Physiology and Chronic Health Evaluation 2, age, and comorbid conditions that could affect SpO2/FiO2. The primary outcome was development of ARDS in the hospital. The secondary outcomes included hospital mortality, hospital day of ARDS development, and hospital day of death.
Results
Of the …
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E Festic, V Bansal, DJ Kor, O Gajic… - Journal of intensive care medicine, 2015