作者
Josef Coresh, Hiddo JL Heerspink, Yingying Sang, Kunihiro Matsushita, Johan Arnlov, Brad C Astor, Corri Black, Nigel J Brunskill, Juan-Jesus Carrero, Harold I Feldman, Caroline S Fox, Lesley A Inker, Areef Ishani, Sadayoshi Ito, Simerjot Jassal, Tsuneo Konta, Kevan Polkinghorne, Solfrid Romundstad, Marit D Solbu, Nikita Stempniewicz, Benedicte Stengel, Marcello Tonelli, Mitsumasa Umesawa, Sushrut S Waikar, Chi-Pang Wen, Jack FM Wetzels, Mark Woodward, Morgan E Grams, Csaba P Kovesdy, Andrew S Levey, Ron T Gansevoort, Lawrence J Appel, Tom Greene, Teresa K Chen, John Chalmers, Hisatomi Arima, Vlado Perkovic, Adeera Levin, Ognjenka Djurdjev, Mila Tang, Joseph Nally, Sankar D Navaneethan, Jesse D Schold, Misghina Weldegiorgis, William G Herrington, Margaret Smith, C Yenchih Hsu, Shih-Jen Hwang, Alex R Chang, H Lester Kirchner, Jamie A Green, Kevin Ho, Angharad Marks, Gordon Prescott, Laura E Clark, Nick Fluck, Varda Shalev, Gabriel Chodick, Peter J Blankestijn, Arjan Van Zuilen, Jan A Van den Brand, Mark J Sarnak, Erwin Bottinger, Girish N Nadkarni, Stephen G Ellis, Rajiv Nadukuru, Marie Metzger, Martin Flamant, Pascal Houillier, Jean-Philippe Haymann, Marc Froissart, Timothy Kenealy, Raina C Elley, John F Collins, Paul L Drury, John K Cuddeback, Elizabeth L Ciemins, Rich Stempniewicz, Robert G Nelson, William C Knowler, Stephen J Bakker, Rupert W Major, James F Medcalf, David Shepherd, Elizabeth Barrett-Connor, Jaclyn Bergstrom, Joachim H Ix, Miklos Z Molnar, Keiichi Sumida, Dick de Zeeuw, Barry Brenner, Abdul R Qureshi, Carl-Gustaf Elinder, Bjorn Runesson, Marie Evans, Marten Segelmark, Maria Stendahl, Staffan Schön, David M Naimark, Navdeep Tangri, Maneesh Sud, Atsushi Hirayama, Kazunobu Ichikawa, Henk JG Bilo, Gijs WD Landman, Kornelis JJ Van Hateren, Nanne Kleefstra, Stein I Hallan, Shoshana H Ballew, Jingsha Chen, Lucia Kwak, Aditya Surapaneni, Hans-Henrik Parving, Roger A Rodby, Richard D Rohde, Julia B Lewis, Edmund Lewis, Ronald D Perrone, Kaleab Z Abebe, Fan F Hou, Di Xie, Lawrence G Hunsicker, Enyu Imai, Fumiaki Kobayashi, Hirofumi Makino, Giuseppe Remuzzi, Piero Ruggenenti, Kai-Uwe Eckardt, Hrefna Gudmundsdottir, Romaldas Maciulaitis, Tom Manley, Kimberly Smith, Norman Stockbridge, Aliza Thompson, Thorsten Vetter, Kerry Willis, Luxia Zhang
发表日期
2019/2/1
期刊
The lancet Diabetes & endocrinology
卷号
7
期号
2
页码范围
115-127
出版商
Elsevier
简介
Background
Change in albuminuria as a surrogate endpoint for progression of chronic kidney disease is strongly supported by biological plausibility, but empirical evidence to support its validity in epidemiological studies is lacking. We aimed to assess the consistency of the association between change in albuminuria and risk of end-stage kidney disease in a large individual participant-level meta-analysis of observational studies.
Methods
In this meta-analysis, we collected individual-level data from eligible cohorts in the Chronic Kidney Disease Prognosis Consortium (CKD-PC) with data on serum creatinine and change in albuminuria and more than 50 events on outcomes of interest. Cohort data were eligible if participants were aged 18 years or older, they had a repeated measure of albuminuria during an elapsed period of 8 months to 4 years, subsequent end-stage kidney disease or mortality follow-up data, and …
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J Coresh, HJL Heerspink, Y Sang, K Matsushita… - The lancet Diabetes & endocrinology, 2019