作者
Lu Zhang, Jiahui Yin, Haiyang Sun, Jiguo Yang, Yuanxiang Liu
发表日期
2023/10/1
期刊
BMJ open
卷号
13
期号
10
页码范围
e074001
出版商
British Medical Journal Publishing Group
简介
Objective
The pathogenesis of depression is related to immune inflammatory response. Atherogenic coefficient (AC) is an important indicator of lipid abnormalities, which can lead to immune inflammatory responses. However, no study has investigated the relationship between AC and depression in adult Americans. Therefore, we investigated this relationship.
Design
This study used a cross-sectional design.
Setting
The National Health and Nutrition Examination Survey (2005–2018) data were used for this study.
Participants
A total of 32 502 participants aged 20 years or older who had complete information for AC and depression were included in this study.
Primary and secondary outcome measures
Depressive symptoms were assessed using the nine-item version of the Patient Health Questionnaire (PHQ-9), with a cut-off point of 9/10 indicating likely depression cases. Weighted logistic regression analyses and the …
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