作者
Grace Gombolay, James Brenton, Jonathan Santoro, Coral Stredny, Ryan Kammeyer, Kristen Fisher, Alexander Sandweiss, Tim Erickson, Varun Kannan, Catherine Otten, NgocHanh Vu, Jennifer Yang, Karla Robles Lopez, Robert Goodrich, Scott Otallah, Janetta Arellano, Andrew Christiana, Claude Steriade, Morgan Morris, Alexandra Kornbluh, Ilana Kahn, Leigh Sepeta, Yike Jiang, Eyal Muscal, Kristy Murray, Manikum Moodley, Duriel Hardy, Mark Gorman
发表日期
2024/4/14
研讨会论文
Neurology
卷号
102
期号
17_supplement_1
页码范围
1248
出版商
Lippincott Williams & Wilkins
简介
Objective
To assess whether initial ancillary tests (brain magnetic resonance imaging-MRI, electroencephalogram-EEG, and/or cerebrospinal fluid-CSF white blood cell count) are abnormal in children with isolated psychiatric symptoms and anti-NMDA receptor encephalitis.
Background
Isolated psychiatric symptoms can be the initial symptom of pediatric anti-NMDA receptor autoimmune encephalitis (pNMDARE). However, the utility of initiating empiric immunotherapy prior to autoantibody test results is poorly understood. Identification of appropriate patients reduces risk of administering unnecessary treatment. Here we assess the characteristics of isolated new onset psychiatric symptoms in pNMDARE.
Design/Methods
This multi-center retrospective cohort study from CONNECT (CONquering Neuroinflammation and Epilepsies ConsorTium) from 14 institutions included children under 18 years old who were …
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G Gombolay, J Brenton, J Santoro, C Stredny… - Neurology, 2024
