作者
Benjamin Rolland, Ali Amad, Emmanuel Poulet, Régis Bordet, Alexandre Vignaud, Rémy Bation, Christine Delmaire, Pierre Thomas, Olivier Cottencin, Renaud Jardri
发表日期
2015/1/1
期刊
Schizophrenia bulletin
卷号
41
期号
1
页码范围
291-299
出版商
Oxford University Press
简介
Both auditory hallucinations (AH) and visual hallucinations may occur in schizophrenia. One of the main hypotheses underlying their occurrence involves the increased activity of the mesolimbic pathway, which links the ventral tegmental area (VTA) and the nucleus accumbens (NAcc). However, the precise contribution of the mesolimbic pathway in hallucinations across various sensory modalities has not yet been explored. We compared the resting-state functional connectivity (rs-FC) of the NAcc among 16 schizophrenia patients with pure AH, 15 with both visuoauditory hallucinations (VAH), and 14 without hallucinations (NoH). A between-group comparison was performed using random-effects ANCOVA (rs-FC of the bilateral NAcc as the dependent variable, groups as the between-subjects factor, age and Positive and Negative Syndrome Scale scores as covariates; q (false discovery …
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