作者
Isabelle Meyts, Giorgia Bucciol, Isabella Quinti, Bénédicte Neven, Alain Fischer, Elena Seoane, Eduardo Lopez-Granados, Carla Gianelli, Angel Robles-Marhuenda, Pierre-Yves Jeandel, Catherine Paillard, Vijay G Sankaran, Yesim Yilmaz Demirdag, Vassilios Lougaris, Alessandro Aiuti, Alessandro Plebani, Cinzia Milito, Virgil ASH Dalm, Kissy Guevara-Hoyer, Silvia Sánchez-Ramón, Liliana Bezrodnik, Federica Barzaghi, Luis Ignacio Gonzalez-Granado, Grant R Hayman, Gulbu Uzel, Leonardo Oliveira Mendonça, Carlo Agostini, Giuseppe Spadaro, Raffaele Badolato, Annarosa Soresina, François Vermeulen, Cedric Bosteels, Bart N Lambrecht, Michael Keller, Peter J Mustillo, Roshini S Abraham, Sudhir Gupta, Ahmet Ozen, Elif Karakoc-Aydiner, Safa Baris, Alexandra F Freeman, Marco Yamazaki-Nakashimada, Selma Scheffler-Mendoza, Sara Espinosa-Padilla, Andrew R Gennery, Stephen Jolles, Yazmin Espinosa, M Cecilia Poli, Claire Fieschi, Fabian Hauck, Charlotte Cunningham-Rundles, Nizar Mahlaoui, Klaus Warnatz, Kathleen E Sullivan, Stuart G Tangye
发表日期
2021/2/1
期刊
Journal of Allergy and Clinical Immunology
卷号
147
期号
2
页码范围
520-531
出版商
Mosby
简介
Background
There is uncertainty about the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in individuals with rare inborn errors of immunity (IEI), a population at risk of developing severe coronavirus disease 2019. This is relevant not only for these patients but also for the general population, because studies of IEIs can unveil key requirements for host defense.
Objective
We sought to describe the presentation, manifestations, and outcome of SARS-CoV-2 infection in IEI to inform physicians and enhance understanding of host defense against SARS-CoV-2.
Methods
An invitation to participate in a retrospective study was distributed globally to scientific, medical, and patient societies involved in the care and advocacy for patients with IEI.
Results
We gathered information on 94 patients with IEI with SARS-CoV-2 infection. Their median age was 25 to 34 years. Fifty-three patients (56 …
学术搜索中的文章
I Meyts, G Bucciol, I Quinti, B Neven, A Fischer… - Journal of Allergy and Clinical Immunology, 2021