作者
Ranga Raman Ganta, Srividya Nasaka, Vijay Gandhi Linga, Sadashivudu Gundeti, Lakshmi Srinivas Maddali, Raghunadha Rao Digumarti
发表日期
2017/7
期刊
Indian Journal of Medical and Paediatric Oncology
卷号
38
期号
03
页码范围
282-286
出版商
Thieme Medical and Scientific Publishers Pvt. Ltd.
简介
Introduction
The Sokal and Hasford (Euro) scores were developed in the chemotherapy and interferon eras and are widely used as prognostic indicators in patients with chronic myeloid leukemia (CML). Recently, European Treatment and Outcome Study (EUTOS) scoring system was introduced. Data on risk stratification in pediatric CML population was lacking due to its rarity (<3%).
Objective
To study the effectiveness in predicting the response and outcome with three prognostic scores in pediatric CML-chronic phase patients on front line Imatinib.
Materials and Methods
We retrospectively analyzed the hospital records of newly diagnosed CML CP patients (aged ≤18 years) from 2006 to 2010 for their risk score, cytogenetic response at 18 months and event free survival (EFS) at the end of 4 years. Events include loss of hematological response, loss of cytological response, progression to accelerated/blast phase …
引用总数
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