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The aqueous ethanolic extract of "Azadirachta indicia" bark was evaluated for its ability to ameliorate aflatoxin induced damage to blood cells and hepatotoxicity in albino mice. Six groups (I-VI) of mice were used in this study. Mice in group I were exposed to aflatoxin-free feed only while those in group II were fed with aflatoxin contaminated feed only for 3 weeks. Groups III-V were exposed to aflatoxin contaminated feed for three weeks each and then treated interperitonially with 0.25 mL of 50, 100 and 150 mg/kgbwt aqueous ethanolic extract of "A. indica", respectively, at one dose daily for 7 days. Group VI was fed aflatoxin-free feed for three weeks and then administered with 150 mg/kgbwt "A. indica" extract to ascertain the effect of this concentration of the extract on the mice. Aflatoxin was immunosuppressive, leading to a reduction in PCV, WBC, neutrophile and lymphocyte counts in group II mice as compared to …