作者
Jui-Hsin Su, Yen-Ju Tseng, Hsin-Hui Huang, Atallah F Ahmed, Chung-Kuang Lu, Yang-Chang Wu, Jyh-Horng Sheu
发表日期
2006/5/26
期刊
Journal of natural products
卷号
69
期号
5
页码范围
850-852
出版商
American Chemical Society
简介
Chemical investigations on the EtOAc-soluble fractions from the EtOH extract of two Formosan soft corals afforded two new 9,11-secosteroids, 3β,11-dihydroxy-5β,6β-epoxy-24-methylene-9,11-secocholestan-9-one (1) and 3β,11-dihydroxy-24-methylene-9,11-secocholestan-9-one (2), from Sinularia lochmodes and Sinularia leptoclados, respectively, along with two known analogues (3 and 4) from S. leptoclados. The structures of the new metabolites were elucidated on the basis of extensive spectroscopic analysis and by comparison of their NMR data with those of the known compound 3. The cytotoxicity of 2−4 toward a limited panel of cancer cell lines is also reported.
学术搜索中的文章
JH Su, YJ Tseng, HH Huang, AF Ahmed, CK Lu… - Journal of natural products, 2006