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The proper choice of a venous access for parenteral nutrition (PN) largely depends on nutrient requirements, expected duration of PN and the setting in which PN will be delivered [Steiger 2002, Pittiruti-Hamilton 2009, August 2009, RCN 2010, INS 2011, O'Grady 2011].

Venous access devices (VADs) can be classified as central (when the tip of the catheter lies between the lower third of the superior vena cava and the upper region of the right atrium) or peripheral (in all the other instances; though, for the purpose of infusion of hyperosmolar solutions and PN, the position of the tip in the inferior vena cava–typically after cannulation of the femoral vein-is also sometimes regarded as' central'). Concerning their performance in terms of duration, they can be classified as short-term, medium-term, or long-term [Gallieni 2008].