作者
F Bozzetti, P Cotogni, S Lo Vullo, Loris Pironi, Daniele Giardiello, Luigi Mariani
发表日期
2015/11/1
期刊
Annals of Oncology
卷号
26
期号
11
页码范围
2335-2340
出版商
Elsevier
简介
Background
The use of home parenteral nutrition (HPN) in incurable cancer patients is extremely varied across different countries and institutions. In order to assess the clinical impact implied, we previously conducted a survey of incurable cancer patients receiving HPN, which shows that survival was markedly affected by Karnofsky performance status (KPS), tumor spread, Glasgow prognostic score (GPS) and tumor site. The aim of this study was to develop a nomogram incorporating the above factors for survival prediction.
Patients and methods
We gathered a series of 579 patients, all receiving HPN, which was randomly split into a training and a testing sample. Using Cox proportional hazard regression modeling, a nomogram was built in the training sample, in order to estimate median survival or survival probability at 3 and 6 months according to individual patient characteristics. The nomogram performance was …
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