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Whether peripherally inserted central catheters (PICCs) are appropriate as safe and durable venous access devices (VADs) is still controversial. The aim of this 7‐year, prospective cohort study was to compare the incidence rate differences of catheter‐related complications (CRCs) among 4 types of central VADs in cancer patients receiving home parenteral nutrition (HPN).

We enrolled all adult cancer outpatients who were candidates for HPN and who had a central VAD inserted during the study period, focusing on the incidence rate of CRCs.

We evaluated 854 central VADs (401 PICCs, 137 nontunneled centrally inserted central catheters [CICCs], 118 tunneled‐cuffed CICCs, and 198 ports) in 761 patients, for a total of 169,116 catheter‐days. Overall, the rate of total CRCs was 1.08/1000 catheter‐days. The incidence of catheter‐related bloodstream infections was low (0.29/1000 …