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5G is a critical infrastructure that will connect the whole society and bridge other critical infrastructure systems. Thus, cybersecurity emerges as crucial tenet within the 5G pathway. In this article, we discuss the concept of agile security within a 5G infrastructure taking into account two of its major technologies: Mobile Edge Computing (MEC) and Network Functions Virtualization (NFV). In this sense, we first discuss the 5G-driven MEC deployment from a NFV perspective. Secondly, we present the concept of agile security and how it can be embedded in the daily activities of mobile network operators (MNOs). Thirdly, we discuss risk management as a key element of the agile security framework. To illustrate its application, we propose the design of an agile security risk-aware edge server mechanism for 5G driven MEC deployment, which uses multiple thresholds and a load-balancing security control to mitigate the risks …