作者
Catherine F Poh, Samson P Ng, P Michele Williams, Lewei Zhang, Denise M Laronde, Pierre Lane, Calum MacAulay, Miriam P Rosin
发表日期
2007/1
期刊
Head & Neck: Journal for the Sciences and Specialties of the Head and Neck
卷号
29
期号
1
页码范围
71-76
出版商
Wiley Subscription Services, Inc., A Wiley Company
简介
Background
A considerable proportion of oral cancer and precancer is not clinically apparent and could contribute significantly to the late diagnosis and high mortality of oral cancer. A simple method to identify such occult change is needed.
Methods
Patients in the Oral Dysplasia Clinics at British Columbia are currently being examined with a simple hand‐held device that permits the direct visualization of alterations to autofluorescence in the oral cavity. Tissue showing loss of autofluorescence is biopsied.
Results
We present 3 representative cases in which occult lesions were identified with fluorescence visualization during longitudinal follow‐up, resulting in the diagnosis of a primary dysplasia in case 1, a second primary cancer in case 2, and cancer recurrence in case 3.
Conclusions
This is the first report of the diagnosis of occult oral disease using a simple noninvasive device. These early examples …
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CF Poh, SP Ng, PM Williams, L Zhang, DM Laronde… - Head & Neck: Journal for the Sciences and Specialties …, 2007