作者
Dao Ngoc Hien Tam, Gehad Mohamed Tawfik, Amr Ehab El-Qushayri, Ghaleb Muhammad Mehyar, Sedralmontaha Istanbuly, Sedighe Karimzadeh, Vo Linh Tu, Ranjit Tiwari, Truong Van Dat, Phuong Thuy Viet Nguyen, Kenji Hirayama, Nguyen Tien Huy
发表日期
2020/12
来源
Malaria Journal
卷号
19
页码范围
1-12
出版商
BioMed Central
简介
Background
Despite noticeable improvement in anti-malarial treatment, rapid growth of resistant malaria strains points out the need for continuous development of novel anti-malarials to fight the disastrous infection. Haemozoin is considered as a novel inhibitory pathway for new anti-malarial drugs, therefore, this study aimed to systematically review all articles investigating the correlation between anti-malarial and anti-haemozoin activities of anti-malarial compounds.
Methods
A literature search was conducted on 22 October 2017 in eight databases for relevant in vitro articles reporting the correlation between anti-malarial and anti-haemozoin of anti-malarial compounds, based on the constructed search terms and inclusion criteria. ToxRtool was used to assess quality of each study.
Results
A total of ten articles were included in the review. In vitro anti-malarial and anti-haemozoin activity had a good correlation …
学术搜索中的文章
DNH Tam, GM Tawfik, AE El-Qushayri, GM Mehyar… - Malaria Journal, 2020