作者
Jean-Pierre Gangneux, Eric Dannaoui, Arnaud Fekkar, Charles-Edouard Luyt, Françoise Botterel, Nicolas De Prost, Jean-Marc Tadié, Florian Reizine, Sandrine Houzé, Jean-François Timsit, Xavier Iriart, Béatrice Riu-Poulenc, Boualem Sendid, Saad Nseir, Florence Persat, Florent Wallet, Patrice Le Pape, Emmanuel Canet, Ana Novara, Melek Manai, Estelle Cateau, Arnaud W Thille, Sophie Brun, Yves Cohen, Alexandre Alanio, Bruno Mégarbane, Muriel Cornet, Nicolas Terzi, Lionel Lamhaut, Estelle Sabourin, Guillaume Desoubeaux, Stephan Ehrmann, Christophe Hennequin, Guillaume Voiriot, Gilles Nevez, Cécile Aubron, Valérie Letscher-Bru, Ferhat Meziani, Marion Blaize, Julien Mayaux, Antoine Monsel, Frédérique Boquel, Florence Robert-Gangneux, Yves Le Tulzo, Philippe Seguin, Hélène Guegan, Brice Autier, Matthieu Lesouhaitier, Romain Pelletier, Sorya Belaz, Christine Bonnal, Antoine Berry, Jordan Leroy, Nadine François, Jean-Christophe Richard, Sylvie Paulus, Laurent Argaud, Damien Dupont, Jean Menotti, Florent Morio, Marie Soulié, Carole Schwebel, Cécile Garnaud, Juliette Guitard, Solène Le Gal, Dorothée Quinio, Jeff Morcet, Bruno Laviolle, Jean-Ralph Zahar, Marie-Elisabeth Bougnoux
发表日期
2022/2/1
期刊
The Lancet Respiratory Medicine
卷号
10
期号
2
页码范围
180-190
出版商
Elsevier
简介
Background
Patients with severe COVID-19 have emerged as a population at high risk of invasive fungal infections (IFIs). However, to our knowledge, the prevalence of IFIs has not yet been assessed in large populations of mechanically ventilated patients. We aimed to identify the prevalence, risk factors, and mortality associated with IFIs in mechanically ventilated patients with COVID-19 under intensive care.
Methods
We performed a national, multicentre, observational cohort study in 18 French intensive care units (ICUs). We retrospectively and prospectively enrolled adult patients (aged ≥18 years) with RT-PCR-confirmed SARS-CoV-2 infection and requiring mechanical ventilation for acute respiratory distress syndrome, with all demographic and clinical and biological follow-up data anonymised and collected from electronic case report forms. Patients were systematically screened for respiratory fungal …
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JP Gangneux, E Dannaoui, A Fekkar, CE Luyt… - The Lancet Respiratory Medicine, 2022