作者
Veda N Giri, Todd M Morgan, David S Morris, Jacob E Berchuck, Colette Hyatt, Mary‐Ellen Taplin
发表日期
2022/7
来源
CA: a cancer journal for clinicians
卷号
72
期号
4
页码范围
360-371
简介
Inherited genetic mutations can significantly increase the risk for prostate cancer (PC), may be associated with aggressive disease and poorer outcomes, and can have hereditary cancer implications for men and their families. Germline genetic testing (hereditary cancer genetic testing) is now strongly recommended for patients with advanced/metastatic PC, particularly given the impact on targeted therapy selection or clinical trial options, with expanded National Comprehensive Cancer Network guidelines and endorsement from multiple professional societies. Furthermore, National Comprehensive Cancer Network guidelines recommend genetic testing for men with PC across the stage and risk spectrum and for unaffected men at high risk for PC based on family history to identify hereditary cancer risk. Primary care is a critical field in which providers evaluate men at an elevated risk for PC, men living with PC, and …
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VN Giri, TM Morgan, DS Morris, JE Berchuck, C Hyatt… - CA: a cancer journal for clinicians, 2022