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The synthesis of nitrogen-doped carbon dots (N@CDs) was accomplished by a hydrothermal process using meta- phenylenediamine as a source of carbon and nitrogen. As prepared N@CDs exhibited bright blue color fluorescence emission (λ_ex = 340 nm and λ_em = 420 nm) with a quantum yield of 12%. Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus were eradicated by N@CDs with a minimum inhibition concentration (MIC) of 1 and 0.75 mg/mL, respectively. The N@CDs were also proven as nanovesicles for drug molecules where the drug release displayed a sustained time-dependent profile at the physiological condition. The release of ciprofloxacin as a model drug was governed by the Korsmeyer-Peppas model, indicating ∼60% of its release from the N@CD conjugated drug system at the physiological pH. Selective analysis of trinitrophenol (TNP), a popular explosive, was …