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Diabetic neuropathy (DN) is the most common and troublesome complication of diabetes mellitus (DM), leading to the greatest morbidity and mortality and resulting in a huge economic burden for diabetes care. 1, 2 It is the most common form of neuropathy in the developed countries of the world, accounts for more hospitalizations than all the other diabetic complications combined, and is responsible for 50% to 75% of nontraumatic amputations. 2, 3 DN is a set of clinical syndromes that affect distinct regions of the nervous system, singly or combined. It may be silent and go undetected while exercising its ravages; or it may present with clinical symptoms and signs that, although nonspecific and insidious with slow progression, also mimic those seen in many other diseases. DN is, therefore, diagnosed by exclusion. Unfortunately both endocrinologists and nonendocrinologists have not been trained to recognize the …