作者
Danping Zheng, Wenshuo Tian, Zhouying Zheng, Jincui Gu, Zhiyong Guo, Xiaoshun He
发表日期
2017/8
期刊
Clinical Transplantation
卷号
31
期号
8
页码范围
e13013
简介
Background
The accuracy of computed tomography (CT) for detecting donor hepatic steatosis (HS) before liver transplantation is not well established.
Methods
A meta‐analysis was performed to determine the accuracy of CT for HS detection in liver donor candidates. Pooled sensitivity, specificity, positive and negative likelihood ratios, hierarchical summary receiver operating characteristic (HSROC) curves, and the area under the curve (AUC) were estimated using HSROC and bivariate random‐effects models.
Results
Twelve studies involving 1782 subjects were eligible for this meta‐analysis. For detecting significant HS (>10%‐30% steatosis in liver pathology) with CT in liver donors, the pooled sensitivity, specificity, positive likelihood ratio, and negative likelihood ratio were 0.81 (95% confidence interval [CI]: 0.70‐0.89), 0.94 (95% CI: 0.90‐0.96), 13.7 (95% CI: 8.1‐23.1), and 0.20 (95% CI: 0.12‐0.33). The …
引用总数
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