作者
Ian H de Boer, Tessa C Rue, Yoshio N Hall, Patrick J Heagerty, Noel S Weiss, Jonathan Himmelfarb
发表日期
2011/6/22
期刊
Jama
卷号
305
期号
24
页码范围
2532-2539
出版商
American Medical Association
简介
Context
Diabetes is the leading cause of kidney disease in the developed world. Over time, the prevalence of diabetic kidney disease (DKD) may increase due to the expanding size of the diabetes population or decrease due to the implementation of diabetes therapies.
Objective
To define temporal changes in DKD prevalence in the United States.
Design, Setting, and Participants
Cross-sectional analyses of the Third National Health and Nutrition Examination Survey (NHANES III) from 1988-1994 (N = 15 073), NHANES 1999-2004 (N = 13 045), and NHANES 2005-2008 (N = 9588). Participants with diabetes were defined by levels of hemoglobin A1c of 6.5% or greater, use of glucose-lowering medications, or both (n = 1431 in NHANES III; n = 1443 in NHANES 1999-2004; n = 1280 in NHANES 2005-2008).
Main Outcome Measures
Diabetic kidney disease was defined as diabetes with albuminuria (ratio of …
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IH de Boer, TC Rue, YN Hall, PJ Heagerty, NS Weiss… - Jama, 2011