作者
Reem Binsuwaidan, Engy Elekhnawy, Walaa S Elseady, Walaa A Keshk, Nagwa A Shoeib, Nashwah GM Attallah, Fatma A Mokhtar, Soha R Abd El Hadi, Eman Ahmed, Sameh Magdeldin, Walaa A Negm
发表日期
2022/11/1
期刊
Biomedicine & Pharmacotherapy
卷号
155
页码范围
113763
出版商
Elsevier Masson
简介
Patients with diabetes mellitus often suffer from chronic wounds due to wound healing impairment. Considering the increased prevalence of diabetes, this would predispose significant medical, economic, and social problems. These chronic wounds are frequently infected with pathogenic bacteria like Pseudomonas aeruginosa, which complicates the situation and makes the wound healing process more difficult. Therefore, there is a high need for therapeutic alternatives to the currently available treatments. Plants are vital sources of many bioactive compounds with multiple biological activities. We elucidated the wound healing possibility and antibacterial effect of Cycas thouarsii n-butanol fraction (CTBF) for the first time. Also, CTBF's phytochemical fingerprint was investigated using the LC-MS/MS technology. Interestingly, CTBF revealed antibacterial activity against P. aeruginosa isolates with minimum inhibitory …
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R Binsuwaidan, E Elekhnawy, WS Elseady, WA Keshk… - Biomedicine & Pharmacotherapy, 2022