作者
EL Vos, RA Carr, M Hsu, M Nakauchi, T Nobel, A Russo, A Barbetta, KS Tan, L Tang, D Ilson, GY Ku, AJ Wu, YY Janjigian, SS Yoon, MS Bains, DR Jones, D Coit, D Molena, VE Strong
发表日期
2021/11/1
期刊
British Journal of Surgery
卷号
108
期号
11
页码范围
1332-1340
出版商
Oxford University Press
简介
Background
Trials typically group cancers of the gastro-oesophageal junction (GOJ) with oesophageal or gastric cancer when studying neoadjuvant chemoradiation and perioperative chemotherapy, so the results may not be fully applicable to GOJ cancer. Because optimal neoadjuvant treatment for GOJ cancer remains controversial, outcomes with neoadjuvant chemoradiation versus chemotherapy for locally advanced GOJ adenocarcinoma were compared retrospectively.
Methods
Data were collected from all patients who underwent neoadjuvant treatment followed by surgery for adenocarcinoma located at the GOJ at a single high-volume institution between 2002 and 2017. Postoperative major complications and mortality were compared between groups using Fisher’s exact test. Overall survival (OS) and disease-free survival (DFS) were assessed by log rank test and …
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EL Vos, RA Carr, M Hsu, M Nakauchi, T Nobel… - British Journal of Surgery, 2021