作者
Sheng-Hao Tseng, Alexander Grant, Anthony J Durkin
发表日期
2008/1/14
期刊
Journal of biomedical optics
卷号
13
期号
1
页码范围
014016-014016-7
出版商
Society of Photo-Optical Instrumentation Engineers
简介
We develop a superficial diffusing probe with a source-detector separation that can be used in combination with diffuse optical spectroscopic (DOS) methods to noninvasively determine full-spectrum optical properties of superficial in vivo skin in the wavelength range from 650 to . This new probe uses a highly scattering layer to diffuse photons emitted from a collimated light source and relies on a two-layer diffusion model to determine tissue absorption coefficient and reduced scattering coefficient . By employing the probe to measure two-layer phantoms that mimic the optical properties of skin, we demonstrate that the probe has an interrogation depth of 1 to . We carry out SSFDPM (steady state frequency-domain photon migration) measurements using this new probe on the volar forearm and palm of 15 subjects, including five subjects of African descent, five Asians, and five Caucasians. The …
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SH Tseng, A Grant, AJ Durkin - Journal of biomedical optics, 2008