作者
Peter V Draganov, Hiroyuki Aihara, Michael S Karasik, Saowanee Ngamruengphong, Abdul Aziz Aadam, Mohamed O Othman, Neil Sharma, Ian S Grimm, Alaa Rostom, B Joseph Elmunzer, Salmaan A Jawaid, Donevan Westerveld, Yaseen B Perbtani, Brenda J Hoffman, Alexander Schlachterman, Amanda Siegel, Roxana M Coman, Andrew Y Wang, Dennis Yang
发表日期
2021/6/1
期刊
Gastroenterology
卷号
160
期号
7
页码范围
2317-2327. e2
出版商
WB Saunders
简介
Background and Aims
Endoscopic submucosal dissection (ESD) in Asia has been shown to be superior to endoscopic mucosal resection (EMR) and surgery for the management of selected early gastrointestinal cancers. We aimed to evaluate technical outcomes of ESD in North America.
Methods
We conducted a multicenter prospective study on ESD across 10 centers in the United States and Canada between April 2016 and April 2020. End points included rates of en bloc resection, R0 resection, curative resection, adverse events, factors associated with failed resection, and recurrence post-R0 resection.
Results
Six hundred and ninety-two patients (median age, 66 years; 57.8% were men) underwent ESD (median lesion size, 40 mm; interquartile range, 25–52 mm) for lesions in the esophagus (n = 181), stomach (n = 101), duodenum (n = 11), colon (n = 211) and rectum (n = 188). En bloc, R0, and curative …
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