作者
Annelies Maes, Caroline Weltens, Patrick Flamen, Philippe Lambin, Ria Bogaerts, Xuan Liu, Jan Baetens, Robert Hermans, Walter Van den Bogaert
发表日期
2002/5/1
期刊
Radiotherapy and oncology
卷号
63
期号
2
页码范围
203-211
出版商
Elsevier
简介
Background and purpose: To evaluate (1) parotid function, (2) subjective xerostomia and (3) pattern of relapses after conformal parotid-sparing radiotherapy (RT) for head and neck cancer. (4) To study dose–response curves of parotid glands. Material and methods: From September 1999 to November 2000, 39 head and neck cancer patients requiring bilateral neck RT were treated with a fairly simple conformal RT technique (three-field set-up+anterior lower neck field; two opposed oblique boost fields). The contralateral parotid was spared. Parotid function was assessed by salivary gland scintigraphies performed before, early (median 4 weeks) and late (median 28 weeks) after RT. Xerostomia was monitored by visual analogue scales (VAS) and LENT SOMA scores. Location of locoregional recurrences was studied in relation to the radiation fields. A dose–response curve of parotids was created using logistic …
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A Maes, C Weltens, P Flamen, P Lambin, R Bogaerts… - Radiotherapy and oncology, 2002