作者
A Rabinovich, T Ducruet, SR Kahn, S Shapiro, V Tagalakis, M Johri, I Chagnon, S Solymoss, L Opatrny, MJ Miron, J Kassis, PS Wells, MA Rodger, MJ Kovacs, DR Anderson, E Yeo, S Selby, R Smith, S Schulman, C Kearon, JS Ginsberg, R Hanmiah, T Wong, C Demers, S Desmarais, S Kaatz, S Rathbun, TL Ortel, SOX Trial investigators
发表日期
2018/2/1
期刊
Journal of Thrombosis and Haemostasis
卷号
16
期号
2
页码范围
262-270
出版商
Elsevier
简介
Essentials
- •We developed a prediction model for postthrombotic syndrome (PTS) after deep vein thrombosis (DVT).
- •High risk predictors were iliac vein DVT, BMI>35 and moderate‐severe Villalta category.
- •Patients with a score ≥4 had an odds ratio of 5.9 (95% CI 2.1‐16.6) for PTS.
- •SOX‐PTS score may select DVT patients for close monitoring or aggressive strategies to treat DVT.
Summary: Background
Postthrombotic syndrome (PTS) is a chronic complication that develops in 20–50% of patients after deep vein thrombosis (DVT). Although individual risk factors for PTS have been characterized, the ability to predict which DVT patients are likely to develop PTS remains limited.
Objective
To develop a clinical prediction score for PTS in patients with DVT.
Methods
The derivation cohort consisted of participants in the SOX Trial, a randomized double‐blind placebo‐controlled trial of elastic compression stockings versus …
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A Rabinovich, T Ducruet, SR Kahn, S Shapiro… - Journal of Thrombosis and Haemostasis, 2018