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Today, topical application of sunscreens, containing ultraviolet‐filters (UV‐filters), is preferred protection against adverse effects of ultraviolet radiation. Evidently, use of sunscreens is effective in prevention of sunburns in various models. However, evidence for their protective effects against melanoma skin cancer is less conclusive. Three important observations prompted us to review the animal data and human studies on possible side effects of selected chemical UV‐filters in cosmetics. (1) the utilization of sunscreens with UV‐filters is increasing worldwide; (2) the incidence of the malignant disorder for which sunscreens should protect, malignant melanoma, is rapidly increasing and (3) an increasing number of experimental studies indicating that several UV‐filters might have endocrine disruptive effects. The selected UV‐filters we review in this article are benzophenone‐3 (BP‐3), 3‐benzylidene camphor (3‐BC …