作者
Evangelos K Oikonomou, Damianos G Kokkinidis, Polydoros N Kampaktsis, Eitan A Amir, Thomas H Marwick, Dipti Gupta, Paaladinesh Thavendiranathan
发表日期
2019/10/1
来源
JAMA cardiology
卷号
4
期号
10
页码范围
1007-1018
出版商
American Medical Association
简介
Importance
Echocardiographic left ventricular global longitudinal strain (GLS) detects early subclinical ventricular dysfunction and can be used in patients receiving potentially cardiotoxic chemotherapy. A meta-analysis of the prognostic value of GLS for cancer therapy–related cardiac dysfunction (CTRCD) has not been performed, to our knowledge.
Objective
To explore the prognostic value of GLS for the prediction of CTRCD.
Data Sources
Systematic search of the MEDLINE, Embase, Scopus, and the Cochrane Library databases from database inception to June 1, 2018.
Study Selection
Cohort studies assessing the prognostic or discriminatory performance of GLS before or during chemotherapy for subsequent CTRCD.
Data Extraction and Synthesis
Random-effects meta-analysis and hierarchical summary receiver operating characteristic curves (HSROCs) were used to summarize the prognostic and discriminatory …
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EK Oikonomou, DG Kokkinidis, PN Kampaktsis… - JAMA cardiology, 2019