作者
Laura Bucci, Francesca Garuti, Barbara Lenzi, Anna Pecorelli, Fabio Farinati, Edoardo G Giannini, Alessandro Granito, Francesca Ciccarese, Gian Lodovico Rapaccini, Maria Di Marco, Eugenio Caturelli, Marco Zoli, Franco Borzio, Rodolfo Sacco, Calogero Cammà, Roberto Virdone, Fabio Marra, Martina Felder, Filomena Morisco, Luisa Benvegnù, Antonio Gasbarrini, Gianluca Svegliati‐Baroni, Francesco Giuseppe Foschi, Gabriele Missale, Alberto Masotto, Gerardo Nardone, Antonio Colecchia, Mauro Bernardi, Franco Trevisani, Italian Liver Cancer (ITA. LI. CA) group, Maurizio Biselli, Paolo Caraceni, Alessandro Cucchetti, Marco Domenicali, Annagiulia Gramenzi, Donatella Magalotti, Lucia Napoli, Giulia Negrini, Fabio Piscaglia, Carla Serra, Francesco Tovoli, Filippo Marafatto, Francesca Murer, Giulia Peserico, Caterina Pozzan, Veronica Vanin, Alessandro Moscatelli, Gaia Pellegatta, Antonino Picciotto, Vincenzo Savarino, Paolo Del Poggio, Stefano Olmi, Nicoletta de Matthaeis, Claudia Balsamo, Elena Vavassori, Paola Roselli, Serena Dell’Isola, Anna Maria Ialungo, Elena Rastrelli, Maria Rosa Barcellona, Giuseppe Cabibbo, Andrea Costantino, Marcello Maida, Andrea Affronti, Andrea Mega, Emanuele Rinninella, Valeria Mismas, Anna Chiara Dall’Aglio, Valentina Feletti, Arianna Lanzi, Federica Mirici Cappa, Elga Neri, Giuseppe Francesco Stefanini, Stefano Tamberi, Elisabetta Biasini, Emanuela Porro, Maria Guarino, Stefano Gemini, Laura Schiadà, Maria Chiaramonte, Fabiana Marchetti, Matteo Valerio, Alberta Cappelli, Rita Golfieri, Cristina Mosconi, Matteo Renzulli, Piero Coccoli, Marco Sanduzzi Zamparelli, Sami Aburas, Andrea Lorenzo Inghilesi
发表日期
2017/2
期刊
Liver International
卷号
37
期号
2
页码范围
259-270
简介
Background & Aims
Epidemiology of hepatocellular carcinoma is changing worldwide. This study aimed at evaluating the changing scenario of aetiology, presentation, management and prognosis of hepatocellular carcinoma in Italy during the last 15 years.
Methods
Retrospective analysis of the ITA.LI.CA (Italian Liver Cancer) database including 5192 hepatocellular carcinoma patients managed in 24 centres from 2000 to 2014. Patients were divided into three groups according to the date of cancer diagnosis (2000–2004, 2005–2009 and 2010–2014).
Results
The main results were as follows: (i) progressive patient aging; (ii) progressive expansion of non‐viral cases and, namely, of “metabolic” hepatocellular carcinomas; (iii) increasing proportion of hepatocellular carcinoma diagnosed during a correct (semi‐annual) surveillance programme; (iv) favourable cancer stage migration; (v) increased use of …
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L Bucci, F Garuti, B Lenzi, A Pecorelli, F Farinati… - Liver International, 2017