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Marginal adaptation is important for the long-term success of dental restorations. Data on the marginal discrepancy of zirconia-based fixed dental prostheses made with different computer-aided design/computer-aided manufacturing technology is needed.

The purpose of this study was to evaluate the marginal adaptation of different zirconia 3-unit fixed dental prostheses at different fabrication stages and after artificial aging.

Twenty-four zirconia 3-unit fixed dental prostheses (DCS, Procera, and VITA YZ-Cerec; n=8) were fabricated using different manufacturing systems and conventionally cemented with glass ionomer cement on human teeth. Each group was aged in a masticatory simulator with thermal cycling. The marginal gaps were examined on epoxy replicas for frameworks and for restorations before and after cementation, and after …