作者
Ole Raaschou-Nielsen, Rob Beelen, Meng Wang, Gerard Hoek, Zorana Jovanovic Andersen, Barbara Hoffmann, Massimo Stafoggia, E Samoli, Gudrun Weinmayr, Konstantina Dimakopoulou, Mark Nieuwenhuijsen, Wei W Xun, P Fischer, Kirsten Thorup Eriksen, Mette Sørensen, Anne Tjønneland, F Ricceri, Kees de Hoogh, T Key, Marloes Eeftens, PH Peeters, H Bas Bueno-de-Mesquita, Kees Meliefste, Bente Oftedal, PE Schwarze, Per Nafstad, Claudia Galassi, Enrica Migliore, Andrea Ranzi, Giulia Cesaroni, Chiara Badaloni, F Forastiere, Johanna Penell, U De Faire, Michal Korek, N Pedersen, C-G Östenson, Gören Pershagen, Laura Fratiglioni, Hans Concin, G Nagel, Andrea Jaensch, Alex Ineichen, Alessio Naccarati, M Katsoulis, A Trichpoulou, Menno Keuken, Aleksandra Jedynska, Ingeborg M Kooter, J Kukkonen, B Brunekreef, RS Sokhi, K Katsouyanni, P Vineis
发表日期
2016/2/1
期刊
Environment international
卷号
87
页码范围
66-73
出版商
Pergamon
简介
Background
Particulate matter (PM) air pollution is a human lung carcinogen; however, the components responsible have not been identified. We assessed the associations between PM components and lung cancer incidence.
Methods
We used data from 14 cohort studies in eight European countries. We geocoded baseline addresses and assessed air pollution with land-use regression models for eight elements (Cu, Fe, K, Ni, S, Si, V and Zn) in size fractions of PM2.5 and PM10. We used Cox regression models with adjustment for potential confounders for cohort-specific analyses and random effect models for meta-analysis.
Results
The 245,782 cohort members contributed 3,229,220 person–years at risk. During follow-up (mean, 13.1 years), 1878 incident cases of lung cancer were diagnosed. In the meta-analyses, elevated hazard ratios (HRs) for lung cancer were associated with all elements except V; none was …
学术搜索中的文章
O Raaschou-Nielsen, R Beelen, M Wang, G Hoek… - Environment international, 2016