作者
Steven P Miller, Donna M Ferriero, Carol Leonard, Robert Piecuch, David V Glidden, J Colin Partridge, Marta Perez, Pratik Mukherjee, Daniel B Vigneron, A James Barkovich
发表日期
2005/11/1
期刊
The Journal of pediatrics
卷号
147
期号
5
页码范围
609-616
出版商
Mosby
简介
OBJECTIVE
To determine the neurodevelopmental outcome of prematurely born newborns with magnetic resonance imaging (MRI) abnormalities.
STUDY DESIGN
A total of 89 prematurely born newborns (median age 28 weeks postgestation) were studied with MRI when stable for transport to MRI (median age, 32 weeks postgestation); 50 newborns were studied again near term age (median age, 37 weeks). Neurodevelopmental outcome was determined at 18 months adjusted age (median) using the Mental Development Index (Bayley Scales Infant Development II) and a standardized neurologic exam.
RESULTS
Of 86 neonatal survivors, outcome was normal in 51 (59%), borderline in 22 (26%), and abnormal in 13 (15%). Moderate/severe MRI abnormalities were common on the first (37%) and second (32%) scans. Abnormal outcome was associated with increasing severity of white matter injury …
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SP Miller, DM Ferriero, C Leonard, R Piecuch… - The Journal of pediatrics, 2005