作者
Jeffrey S Berger, Laine Elliott, Dianne Gallup, Matthew Roe, Christopher B Granger, Paul W Armstrong, R John Simes, Harvey D White, Frans Van de Werf, Eric J Topol, Judith S Hochman, L Kristin Newby, Robert A Harrington, Robert M Califf, Richard C Becker, Pamela S Douglas
发表日期
2009/8/26
期刊
Jama
卷号
302
期号
8
页码范围
874-882
出版商
American Medical Association
简介
Context
Conflicting information exists about whether sex differences modulate short-term mortality following acute coronary syndromes (ACS).
Objectives
To investigate the relationship between sex and 30-day mortality in ACS, and to determine whether this relationship was modified by clinical syndrome or coronary anatomy using a large database across the spectrum of ACS and adjusting for potentially confounding clinical covariates.
Design, Setting, and Participants
A convenience sample of patients pooled from 11 independent, international, randomized ACS clinical trials between 1993 and 2006 whose databases are maintained at the Duke Clinical Research Institute, Durham, North Carolina. Of 136 247 patients, 38 048 (28%) were women; 102 004 (26% women) with ST-segment elevation myocardial infarction (STEMI), 14 466 (29% women) with non-STEMI (NSTEMI), and 19 777 (40% women) with unstable …
引用总数
学术搜索中的文章
JS Berger, L Elliott, D Gallup, M Roe, CB Granger… - Jama, 2009