作者
Panayiotis Kouis, Emmanouil Galanakis, Paraskevi Kinni, Eleni Michaelidou, Antonis Michanikou, Helen Demetriou, Maria G Kakkoura, Pinelopi Anagnostopoulou, Konstantinos Pitsios, Stafania I Papatheodorou, Petros Koutrakis, Panayiotis K Yiallouros
发表日期
2023/9/9
来源
European Respiratory Journal
卷号
62
期号
suppl 67
出版商
European Respiratory Society
简介
Background: Desert dust storm (DDS) events have been associated with increased morbidity among children with asthma. The MEDEA randomised trial assessed the impact of indoor air filtration and other exposure reduction recommendations on asthma symptom control, lung function and airway inflammation among children with asthma during high DDS season in Cyprus and Greece.
Methods: Schoolchildren with asthma aged 6-11 years were randomised into three groups: (a) No Intervention (controls) (b) Outdoor Intervention (early warning dissemination, guidance to stay indoors and limit outdoor physical activity), (c) Combined Intervention (same as (b) in combination with indoor air purification in households and classrooms. Monthly asthma symptom control was quantified using the childhood Asthma Control Test (c-ACT), while lung function (FEV1, FVC) and Fractional exhaled Nitric Oxide (FeNO …