作者
Helen Pappa, Meena Thayu, Francisco Sylvester, Mary Leonard, Babette Zemel, Catherine Gordon
发表日期
2011/7/1
期刊
Journal of pediatric gastroenterology and nutrition
卷号
53
期号
1
页码范围
11-25
出版商
LWW
简介
Current evidence points to suboptimal bone health in children and adolescents with inflammatory bowel disease (IBD) when compared with their healthy peers. This compromise is evident from diagnosis. The clinical consequences and long-term outcome of this finding are still unknown. The mechanism of suboptimal bone health in children and adolescents with IBD lays mainly in reduced bone formation, but also reduced bone resorption, processes necessary for bone growth. Factors contributing to this derangement are inflammation, delayed growth and puberty, lean mass deficits, and use of glucocorticoids. We recognize that evidence is sparse on the topic of bone health in children and adolescents with IBD. In this clinical guideline, based on current evidence, we provide recommendations on screening and monitoring bone health in children and adolescents with IBD, including modalities to achieve this and …
引用总数
2012201320142015201620172018201920202021202220232024131413815161359168135
学术搜索中的文章
H Pappa, M Thayu, F Sylvester, M Leonard, B Zemel… - Journal of pediatric gastroenterology and nutrition, 2011