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The treatment of infectious diseases remains an imperative issue as a result of a number of factors including arise of newer infectious diseases and growing number of multi-drug resistant microbial pathogens. Because the rate of resistance to current antimicrobial treatment has expanded seriously, the discovery of new antimicrobial agents or change for the bioactivity of the current medications is an important task. Huge numbers of the normally occurring furans have demonstrated fascinating natural activities, for example, antimicrobial activity. Also, various hydrazide-hydrazone derivatives have been asserted to have intriguing bioactivity like antibacterial activity. Furthermore; thiazole derivatives are a critical class of heterocyclic compounds. They possess a critical position in medicinal chemistry, displaying an extensive variety of bioactivities such as antibacterial and antifungal. Thus, in this study we reported the …