作者
Job FM van Boven, Niels H Chavannes, Thys van der Molen, Maureen PMH Rutten-van Mölken, Maarten J Postma, Stefan Vegter
发表日期
2014/1/1
来源
Respiratory medicine
卷号
108
期号
1
页码范围
103-113
出版商
WB Saunders
简介
Background
Medication for Chronic Obstructive Pulmonary Disease (COPD) has shown to substantially reduce symptoms and slow progression of disease. However, non-adherence to medication is common and associated with worsened clinical and economic outcomes.
Objective
The objective of this study was to perform a systematic review of published literature to assess the impact of non-adherence to COPD medication on clinical and economic outcomes.
Methods
A search in PubMed and Web of Science databases was conducted of original studies published from database inception to 2012. Studies must report on the association between adherence to COPD medication and outcomes, published in English in peer-reviewed journals and full texts needed to be available.
Results
Twelve full articles were included in the review. Most studies were retrospective database studies. Seven studies reported on the …
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