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Metabolic Syndrome (MetS) is characterized by abdominal obesity, dyslipidemia, elevated fasting blood glucose (FBG), and hypertension; personalized nutrition counseling and wellness applications have demonstrated positive results for weight management when coupled with high levels of participant engagement and motivation.

In a prospective RCT RDs conducted personalized nutrition counseling using results of targeted sequencing, biomarkers, and expert recommendations to reduce risk for MetS. Treatment Group (TG) received six weekly sessions; Control Group (CG) received a pamphlet of expert recommendations upon randomization. A digital application provided real-time health data capture. Anthropometrics and BP were evaluated at baseline, 6, & 12 wks; biomarkers at baseline & 12 wks. Primary outcome was change in weight at 12 wks. Statistical analyses included descriptives …